Insights into the nature of the microalgal toxins from the Chrysochromulina leadbeateri blooms in Northern Norwegian fjords

Validation of a human saliva model for the determination of leachable monomers and other chemicals from dental materials

Profiling of cyclic di-adenyl and -guanyl nucleotides and their precursors and degradation products in bacteria using LC–MS/MS

Influence of biotic and abiotic factors on prymnesin profiles in three strains of Prymnesium parvum

Identification of Caribbean ciguatoxins from benthic dinoflagellates advances knowledge on toxin chemistry and analysis

3-Epimers of Caribbean ciguatoxins in fish and algae

Pharmacokinetics of a long-acting subcutaneous eprinomectin injection in semi-domesticated reindeer (Rangifer tarandus tarandus) – A pilot study

Identification and cross-species comparison of in vitro phase I brevetoxin (BTX-2) metabolites in northern Gulf of Mexico fish and human liver microsomes by UHPLC-HRMS(/MS)

Presence of 6PPD-quinone in runoff water samples from Norway using a new LC–MS/MS method

Algal ciguatoxin identified as source of ciguatera poisoning in the Caribbean

Fish Skin and Gill Mucus: A Source of Metabolites for Non-Invasive Health Monitoring and Research

Reductive Amination for LC-MS Signal Enhancement and Confirmation of the Presence of Caribbean Ciguatoxin-1 in Fish

Efficacy of Fumonisin Esterase in Piglets as Animal Model for Fumonisin Detoxification in Humans: Pilot Study Comparing Intraoral to Intragastric Administration

Production and stability of Oxygen-18 labeled Caribbean ciguatoxins and gambierones

Acute Toxicity Testing of the Tire Rubber-Derived Chemical 6PPD-quinone on Atlantic Salmon (Salmo salar) and Brown Trout (Salmo trutta)

Unraveling the Ergot Alkaloid and Indole Diterpenoid Metabolome in the Claviceps purpurea Species Complex Using LC-HRMS/MS Diagnostic Fragmentation Filtering

The efficacy and effect on gut microbiota of an aflatoxin binder and a fumonisin esterase using an in vitro simulator of the human intestinal microbial ecosystem (SHIME®)

In Vitro Glucuronidation of Caribbean Ciguatoxins in Fish: First Report of Conjugative Ciguatoxin Metabolites

Modelling the Renal Excretion of the Mycotoxin Deoxynivalenol in Humans in an Everyday Situation

Metabolomics Workflow for Quality Control of Differently-Processed Pre-cooked Chicken Fillets

Impact of Plasma-Activated Water Treatment on Quality and Shelf-Life of Fresh Spinach Leaves Evaluated by Comprehensive Metabolomic Analysis

Investigation of age-related differences in toxicokinetic processes of deoxynivalenol and deoxynivalenol-3-glucoside in weaned piglets

Oxidative Release of Thiol-Conjugated Forms of the Mycotoxin 4-Deoxynivalenol

Investigation of In Vitro Endocrine Activities of Microcystis and Planktothrix Cyanobacterial Strains

LC–HRMS and Chemical Derivatization Strategies for the Structure Elucidation of Caribbean Ciguatoxins: Identification of C-CTX-3 and -4

In Vitro Toxicokinetics and Phase I Biotransformation of the Mycotoxin Penitrem A in Dogs

Toxicokinetic Studies in Piglets Reveal Age-Related Differences in Systemic Exposure to Zearalenone, Zearalenone-14-Glucoside, and Zearalenone-14-Sulfate

Identification and distribution of gene clusters required for synthesis of sphingolipid metabolism inhibitors in diverse species of the filamentous fungus Fusarium

Co-Occurrence and Levels of Mycotoxins in Fish Feeds in Kenya

Microcystins and Microcystis aeruginosa PCC7806 extracts modulate steroidogenesis differentially in the human H295R adrenal model

Integrated Omics in salmon skin mucus for determining consequences of chloramine treatment against parasite infestation

Insights into In Vivo Absolute Oral Bioavailability, Biotransformation, and Toxicokinetics of Zearalenone, α-Zearalenol, β-Zearalenol, Zearalenone-14-glucoside, and Zearalenone-14-sulfate in Pigs

Evidence for Naturally Produced Beauvericins Containing N-Methyl-Tyrosine in Hypocreales Fungi

Novel Microcystins from Planktothrix prolifica NIVA-CYA 544 Identified by LC-MS/MS, Functional Group Derivatization and 15N-labeling

Heteroxanthin as a pigment biomarker for Gonyostomum semen (Raphidophyceae)

Effects and biotransformation of the mycotoxin deoxynivalenol in growing pigs fed with naturally contaminated pelleted grains with and without the addition of Coriobacteriaceum DSM 11798

Prediction of deoxynivalenol toxicokinetics in humans by in vitro-to-in vivo extrapolation and allometric scaling of in vivo animal data

Workflow for the Targeted and Untargeted Detection of Small Metabolites in Fish Skin Mucus

Transfer of Deoxynivalenol (DON) through Placenta, Colostrum and Milk from Sows to Their Offspring during Late Gestation and Lactation

Two Isomeric C16 Oxo-Fatty Acids from the Diatom Chaetoceros karianus Show Dual Agonist Activity towards Human Peroxisome Proliferator-Activated Receptors (PPARs) α/γ

Biotransformation of the mycotoxin enniatin B1 in pigs: A comparative in vitro and in vivo approach

Selectivity of commercial immunoaffinity columns for modified forms of the mycotoxin 4-deoxynivalenol (DON)

Characterization and pro-inflammatory responses of spore and hyphae samples from various mold species

Yew (Taxus) intoxication in free-ranging cervids

Liquid Chromatography Photodiode Array Detection of Hydrogen Sulfide and Methanethiol as Thioacrylates following Nucleophilic Addition to Ethyl Propiolate

Effect of primary processing on the distribution of free and modified Fusarium mycotoxins in naturally contaminated oats

Glutathione-Conjugates of Deoxynivalenol in Naturally Contaminated Grain Are Primarily Linked via the Epoxide Group

Black perithecial pigmentation in Fusarium species is due to the accumulation of 5-deoxybostrycoidin-based melanin

Correction to Enzyme-Assisted Synthesis and Structural Characterization of the 3-, 8-, and 15-Glucuronides of Deoxynivalenol

Preparation and Characterization of Cysteine Adducts of Deoxynivalenol

A European Database of Fusarium graminearum and F. culmorum Trichothecene Genotypes

Characterization of Deoxynivalenol-Glutathione Conjugates Using Nuclear Magnetic Resonance Spectroscopy and Liquid Chromatography-High-Resolution Mass Spectrometry

Presence of Fusarium Species and Other Toxigenic Fungi in Malting Barley and Multi-Mycotoxin Analysis by Liquid Chromatography-High-Resolution Mass Spectrometry

Profiling of 3-hydroxy fatty acids as environmental markers of endotoxin using liquid chromatography coupled to tandem mass spectrometry

Fast and sensitive LC-MS/MS method measuring human mycotoxin exposure using biomarkers in urine

Biotransformation of zearalenone and zearalenols to their major glucuronide metabolites reduces estrogenic activity

Mycotoxins and other fungal metabolites in grain dust from Norwegian grain elevators and compound feed mills

Negård, M., Uhlig, S., Kauserud, H., Andersen, T., Høiland, K., Vrålstad, T. (2015) Indole-alkaloid profiles in Norwegian Claviceps purpurea populations - relationships between chemoraces, genetic groups and ecology, Toxins, 7, 1431–1456.

Publications before 2015

Presence of enniatin B and its hepatic metabolites in plasma and liver samples from broilers and eggs from laying hens

Indole-diterpenoid profiles of Claviceps paspali and Claviceps purpurea from high-resolution Fourier transform Orbitrap mass spectrometry

Bioassay-guided fractionation of extracts from Easter lily (Lilium longiflorum) flowers reveals unprecedented structural variability of steroidal glycoalkaloids

Enzyme-assisted synthesis and structural characterization of the 3-, 8-, and 15-glucuronides of deoxynivalenol

Šarkanj, B., Warth, B., Uhlig, S., Abia, W.A., Sulyok, M., Klapec, T., Krska, R., Banjari, I. (2013) Assessment of mycotoxin exposure in Croatian pregnant women by a multi-biomarker approach, Food and Chemical Toxicology, 62, 231¬–237.

Faces of a Changing Climate: Semi-Quantitative Multi-Mycotoxin Analysis of Grain Grown in Exceptional Climatic Conditions in Norway

Busk, Ø.L., Frizzell, C., Verhagen, S., Uhlig, S., Conolly, L., Ropstad, E. and Sørlie, M. (2012) Cytosol protein regulation in H295R steroidogenesis model induced by the zearalenone metabolites, - and -zearalenol, Toxicon, 59, 17–24.

Fusaproliferin, beauvericin and enniatins: Occurrence in food-A review

Identification of early fumonisin biosynthetic intermediates by inactivation of the FUM6 gene in Fusarium verticillioides

Isolation and structure elucidation of secopenitrem D, an indole alkaloid from Penicillium crustosum Thom

Ergosedmine, a new peptide ergot alkaloid (ergopeptine) from the ergot fungus, Claviceps purpurea parasitizing Calamagrostis arundinacea

LC–MS–MS Determination of Gizzerosine in Poultry Feed

In vitro phase I metabolism of the depsipeptide enniatin B

In vitro metabolism of the mycotoxin enniatin B in different species and cytochrome p450 enzyme phenotyping by chemical inhibitors

Phomenins and fatty acids from Alternaria infectoria

Electron ionisation mass spectrometry of the pentafluoropropionate esters of trichothecene analogues and culmorin compounds from Fusarium species

Enniatin B 1 is a substrate of intestinal P-glycoprotein, multidrug resistance-associated protein 2 and breast cancer resistance protein

Structural studies on minor enniatins from Fusarium sp. VI 03441: novel N-methyl-threonine containing enniatins

What about the 'other' Fusarium mycotoxins?

Indole-diterpenes and ergot alkaloids in Cynodon dactylon (Bermuda grass) infected with Claviceps cynodontis from an outbreak of tremors in cattle

Toxicity testing of saponin-containing Yucca schidigera Roetzl. juice in relation to hepato- and nephrotoxicity of Narthecium ossifragum (L.) Huds

Uhlig, S., Ivanova, L., Bernhoft, A. and Eriksen, G.S. (2008) 2-Amino-14,16-dimethyloctadecan-3-ol: in vitro bioactivity and bio-production by the fungus Fusarium avenaceum (syn. F. arthrosporioides), World Mycotoxin Journal, 1, 37–46.

A bioassay for the simultaneous measurement of metabolic activity, membrane integrity, and lysosomal activity in cell cultures

Lactam ergot alkaloids (ergopeptams) as predominant alkaloids in sclerotia of Claviceps purpurea from Norwegian wild grasses

Fusarium avenaceum -- the North European situation

Identification of cytotoxic constituents of Narthecium ossifragum using bioassay-guided fractionation

Ergot alkaloids in Norwegian wild grasses: a mass spectrometric approach

Beauvericin and enniatins A, A1, B and B1 in Norwegian grain: A survey

Cytotoxicity of enniatins A, A1, B, B1, B2 and B3 from Fusarium avenaceum

Multiple regression analysis as a tool for the identification of relations between semi-quantitative LC-MS data and cytotoxicity of extracts of the fungus Fusarium avenaceum (syn. F. arthrosporioides)

Identification of cytotoxic principles from Fusarium avenaceum using bioassay-guided fractionation

2-Amino-14,16-dimethyloctadecan-3-ol, a new sphingosine analogue toxin in the fungal genus Fusarium

Moniliformin in Norwegian grain

Determination of beauvericin and four other enniatins in grain by liquid chromatography-mass spectrometry

Bernhoft, A., Torp, M., Clasen, P.-E., Uhlig, S. and Heier, B. (2004) Less Fusarium infection and mycotoxins in organically than in conventionally grown grain. In: Geomedical problems in organic agriculture (Steinnes E, ed.). Proceedings of a symposium held at the Norwegian Academy of Science and Letters, Oslo, 16-17 October 2003, pp 87–94.

Mycotoxin production by Fusarium avenaceum strains isolated from Norwegian grain and the cytotoxicity of rice culture extracts to porcine kidney epithelial cells

Ongoing research