Methods for investigating the effects of exposures have evolved from specific endpoint tests to a detailed description of key cellular events that may result in adverse outcomes. These new and more precise understandings of how living cells and organisms respond to specific exposures are being gradually incorporated into standardized test methods for evaluating the biocompatibility of biomaterials.
The webinar is based in part on a recent article co-authored by Jon E. Dahl.
The webinar outlines:
- General strengths and weaknesses of laboratory cell culture methods compared to in vivo studies
- How classical (and still used) methods can result in faulty evaluation of biomaterial safety
- How laboratory methods are evolving to be more precise in predicting clinical outcomes